A comparison of dexmedetomidine versus conventional therapy for sedation and hemodynamic control during carotid endarterectomy performed under regional anesthesia.

@article{McCutcheon2006ACO,
  title={A comparison of dexmedetomidine versus conventional therapy for sedation and hemodynamic control during carotid endarterectomy performed under regional anesthesia.},
  author={Craig A McCutcheon and Ruari M Orme and David J. Scott and Michael J Davies and Desmond P. McGlade},
  journal={Anesthesia and analgesia},
  year={2006},
  volume={102 3},
  pages={668-75}
}
The properties of dexmedetomidine (DEX) that result in titratable sedation and sympathetic modulation suggest that it would be suitable for use during carotid endarterectomy (CEA) performed under regional anesthesia. We performed a randomized, double-blind study in 56 patients having CEA under regional anesthesia and compared hemodynamic control using DEX versus a conventional sedation technique using midazolam and fentanyl standard (STD). Sedation was titrated to a Ramsay Sedation Score of 2-4… CONTINUE READING

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