A comparison of allografting with autografting for newly diagnosed myeloma.

  title={A comparison of allografting with autografting for newly diagnosed myeloma.},
  author={B. Bruno and M. Rotta and F. Patriarca and N. Mordini and B. Allione and F. Carnevale-Schianca and L. Giaccone and R. Sorasio and P. Omede' and I. Baldi and S. Bringhen and M. Massaia and M. Aglietta and A. Levis and A. Gallamini and R. Fanin and A. Palumbo and R. Storb and G. Ciccone and M. Boccadoro},
  journal={The New England journal of medicine},
  volume={356 11},
  • B. Bruno, M. Rotta, +17 authors M. Boccadoro
  • Published 2007
  • Medicine
  • The New England journal of medicine
  • BACKGROUND In this trial of the treatment of newly diagnosed multiple myeloma, we compared a protocol that entailed a hematopoietic stem-cell autograft followed by an allograft from an HLA-identical sibling with a protocol of tandem autografts. METHODS We enrolled 162 consecutive patients with newly diagnosed myeloma who were 65 years of age or younger and who had at least one sibling. All patients were initially treated with vincristine, doxorubicin, and dexamethasone, followed by melphalan… CONTINUE READING
    477 Citations

    Paper Mentions

    Interventional Clinical Trial
    The goal of this clinical trial is to study the feasibility and efficacy of anti-CD19/BCMA bispecific chimeric antigen receptors (CARs) T cell therapy for relapsed and refractory… Expand
    ConditionsMultiple Myeloma in Relapse, Multiple Myeloma Progression
    InterventionBiological, Drug
    Long-term outcome of myeloablative allogeneic stem cell transplantation for multiple myeloma.
    • J. Kuruvilla, J. Shepherd, +11 authors K. Song
    • Medicine
    • Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
    • 2007
    • 38
    Unrelated stem cell transplantation for patients with multiple myeloma
    • N. Kröger
    • Medicine
    • Current opinion in hematology
    • 2010
    • 7
    Allogeneic transplantation in multiple myeloma: long-term follow-up and cytogenetic subgroup analysis
    • 10


    Single versus double autologous stem-cell transplantation for multiple myeloma.
    • 965
    • PDF
    Molecular and clinical remissions in multiple myeloma: role of autologous and allogeneic transplantation of hematopoietic cells.
    • P. Corradini, C. Voena, +10 authors A. Pileri
    • Medicine
    • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
    • 1999
    • 241