A comparison of adding liraglutide versus a single daily dose of insulin aspart to insulin degludec in subjects with type 2 diabetes (BEGIN: VICTOZA ADD-ON).

@article{Mathieu2014ACO,
  title={A comparison of adding liraglutide versus a single daily dose of insulin aspart to insulin degludec in subjects with type 2 diabetes (BEGIN: VICTOZA ADD-ON).},
  author={C. Mathieu and H. Rodbard and B. Cariou and Y. Handelsman and A. Philis-Tsimikas and A. M. Ocampo Francisco and A. Rana and B. Zinman},
  journal={Diabetes, obesity & metabolism},
  year={2014},
  volume={16 7},
  pages={
          636-44
        }
}
  • C. Mathieu, H. Rodbard, +5 authors B. Zinman
  • Published 2014
  • Medicine
  • Diabetes, obesity & metabolism
  • AIM Two treatment strategies were compared in patients with type 2 diabetes (T2DM) on basal insulin requiring intensification: addition of once-daily (OD) liraglutide (Lira) or OD insulin aspart (IAsp) with largest meal. METHODS Subjects completing 104 weeks (52-week main trial BEGIN ONCE-LONG + 52-week extension) on insulin degludec (IDeg) OD + metformin with HbA1c ≥ 7.0% (≥53 mmol/mol) were randomized to IDeg+Lira [n = 88, mean HbA1c: 7.7% (61 mmol/mol)] or IDeg+IAsp (n = 89, mean HbA1c: 7… CONTINUE READING

    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    This trial is conducted in Europe and North America. The aim of this trial is to compare the efficacy and safety of adding liraglutide versus addition of insulin aspart with the largest… Expand
    ConditionsDiabetes, Diabetes Mellitus, Type 2
    InterventionDrug

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