A comparison of a novel testosterone bioadhesive buccal system, striant, with a testosterone adhesive patch in hypogonadal males.

@article{Korbonits2004ACO,
  title={A comparison of a novel testosterone bioadhesive buccal system, striant, with a testosterone adhesive patch in hypogonadal males.},
  author={M{\'a}rta Korbonits and Marc Slawik and Derek R Cullen and Richard J. M. Ross and Guenter Karl Stalla and Harald J{\"o}rn Schneider and Martin Reincke and Pierre Marc Gilles Bouloux and Ashley B. Grossman},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2004},
  volume={89 5},
  pages={2039-43}
}
A novel delivery system has been developed for testosterone replacement. This formulation, COL-1621 (Striant), a testosterone-containing buccal mucoadhesive system, has been shown in preliminary studies to replace testosterone at physiological levels when used twice daily. Therefore, the current study compared the steady-state pharmacokinetics and tolerability of the buccal system with a testosterone-containing skin patch (Andropatch or Androderm) in an international multicenter study of a… CONTINUE READING

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