A comparison of DNA damages produced under conditions of direct and indirect action of radiation.

Studies using a 32P-postlabelling assay reveal that at both low and high concentrations of hydroxyl radical scavenger, DNA damage from alpha-irradiation is similar to that from gamma-irradiation. At low concentrations of scavenger the identified damages are predominantly thymine glycol (Tg) and phosphoglycolate (pg) lesions, indicative of indirect hydroxyl… CONTINUE READING