Therapy of human carcinoma xenografts with antibodies to EGFr and HER-2 conjugated to radionuclides emitting low-energy electrons
- M. Jules Mattes, David M. Goldenberg
- European Journal of Nuclear Medicine and…
- 2008
Highly Influenced
5 Excerpts
A comparison of 4 radionuclides conjugated to antibodies for single-cell kill.
- Published 2003 in Journal of nuclear medicine : official…
Abstract
UNLABELLED
We previously found that (67)Ga was more potent and more specific in single-cell kill than other Auger electron emitters and beta-particle emitters, using an anti-CD74 antibody (Ab) (major histocompatibility complex [MHC] class II invariant chain). Because anti-CD74 Abs follow an unusual processing pathway, with rapid delivery in very large… (More)