A comparison of 1-p-acetyldeoxyephedrine and 4-methyl- -ethyl-m-tyramine as to lowering of brain serotonin, and their antagonism by antidepressants.

@article{Dubnick1973ACO,
  title={A comparison of 1-p-acetyldeoxyephedrine and 4-methyl- -ethyl-m-tyramine as to lowering of brain serotonin, and their antagonism by antidepressants.},
  author={Bernard Dubnick and E W Rucki and Andre I. Salama},
  journal={European journal of pharmacology},
  year={1973},
  volume={22 2},
  pages={
          121-8
        }
}
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3 Citations

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Monoamine Oxidase Inhibitors: Animal Pharmacology
TLDR
The animal pharmacology of the monoamine oxidase inhibitors (MAOIs*) has been reviewed previously by Zirkle and Kaiser (1964), Biel et al. (1964) and Jacob and Simon (1968).
Duration of the effects of α‐ethyl‐4‐methyl‐m‐tyramine, (H75/12) on brain 5‐hydroxyindole concentrations in rats
General Pharmacology of Amphetamine-Like Drugs

References

SHOWING 1-10 OF 13 REFERENCES
Selective lowering of brain serotonin by p-acylphenylethylamines.
Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-alpha-ethyl-meta-tyramine.
p-Chloroamphetamine--inhibition of cerebral tryptophan hydroxylase.
Inhibition of the uptake of noradrenaline and 5-hydroxytryptamine by chlorphentermine and chlorimipramine.
Concerning the molecular requirements for the inhibition of the uptake of racemic 3 H-norepinephrine into rat cerebral cortex slices by tricyclic antidepressants and related compounds.
TLDR
The membrane amine pump mechanisms in rabbit aorta and rat cerebral cortex appear to have fundamentally similar properties but differ in at least one respect.
The role of brain serotonin in the mechanism of the central action of reserpine.
TLDR
Studies showing that 5-hydroxytryptophan (5-HTP) in doses that elicit excitation also causes the release of brain NE may remove a key argument against the view that reserpine acts through free 5-HT.
A method for the determination of 5‐hydroxyindolyl‐3‐acetic acid in brain
TLDR
This paper describes a simple and highly sensitive method for the spectrofluorometric determination of 5-HIAA in the brain.
Kinetics of serotonin accumulation into slices from rat brain: relationship to catecholamine uptake.
  • E. Shaskan, S. Snyder
  • Biology, Chemistry
    The Journal of pharmacology and experimental therapeutics
  • 1970
TLDR
The findings suggest that doses of 5-HT administered into the brain in a variety of studies may enter catecholaminergic neurons in significant quantities.
Identification and assay of serotonin in brain.
TLDR
With this method serotonin has been shown to be a normal constituent of brain and may be applied to the measurement of serotonin in other tissues.
SPECIES DIFFERENCES IN THE METABOLISM OF IMIPRAMINE AND DESMETHYLIMIPRAMINE (DMI).
TLDR
Evidence presented in this paper indicates that differences in the metabolism of imipramine and DMI may partially explain the species variations in the pharmacologic response of these "antisedative" compounds.
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