A comparison in rat and mouse heart of the ability of several local anesthetics to inhibit monoamine oxidase.

  • R L Dorris
  • Published 1983 in
    Comparative biochemistry and physiology. C…


Several local anesthetics were examined and compared in rat and mouse heart for MAO inhibitory action. Procaine, chloroprocaine, procainamide and tetracaine were more potent in rat than mouse heart. Piperocaine, cyclomethycaine, hexylcaine and butacaine were somewhat more potent in mouse than rat heart. Propoxycaine and dibucaine were essentially equipotent… (More)


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