A comparison between short ACTH and insulin stress tests for assessing hypothalamo-pituitary-adrenal function.

Abstract

OBJECTIVE Insulin-induced hypoglycaemia is the standard method for assessment of the hypothalamo-pituitary-adrenal (HPA) axis of patients with pituitary or hypothalamic disease. It has been claimed that a normal cortisol response to the 30-minute ACTH stimulation test (AST) obviates the need to perform the insulin stress test (IST) in these patients. The… (More)

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