A comparison between real-time polymerase chain reaction and hybrid capture 2 for human papillomavirus DNA quantitation.

@article{Gravitt2003ACB,
  title={A comparison between real-time polymerase chain reaction and hybrid capture 2 for human papillomavirus DNA quantitation.},
  author={Patti Gravitt and Robert D Burk and Attila T Lorincz and Rolando Herrero and Allan Hildesheim and Mark E. Sherman and Maria Concepcion Bratti and Ana Cecilia Rodr{\'i}guez and Kathy J. Helzlsouer and Mark Schiffman},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2003},
  volume={12 6},
  pages={477-84}
}
Studies investigating human papillomavirus (HPV) viral load as a risk factor in the development of squamous intraepithelial lesions (SILs) and cancer have often yielded conflicting results. These studies used a variety of HPV viral quantitation assays [including the commercially available hybrid capture 2 (HC 2) assay], which differ in their ability to account for differences in cervical cell collection, linear dynamic range of viral load quantitation, and determination of type-specific versus… CONTINUE READING

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