A compare-and-contrast NMR dynamics study of two related RRMs: U1A and SNF.

Abstract

The U1A/U2B″/SNF family of small nuclear ribonucleoproteins uses a phylogenetically conserved RNA recognition motif (RRM1) to bind RNA stemloops in U1 and/or U2 small nuclear RNA (snRNA). RRMs are characterized by their α/β sandwich topology, and these RRMs use their β-sheet as the RNA binding surface. Unique to this RRM family is the tyrosine-glutamine… (More)
DOI: 10.1016/j.bpj.2014.05.026

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