A comparative view on sex determination in medaka

@article{Schartl2004ACV,
  title={A comparative view on sex determination in medaka},
  author={Manfred Schartl},
  journal={Mechanisms of Development},
  year={2004},
  volume={121},
  pages={639-645}
}
  • M. Schartl
  • Published 1 July 2004
  • Biology, Medicine
  • Mechanisms of Development
In fish, an amazing variety of sex determination mechanisms are known, ranging from hermaphroditism to gonochorism and from environmental to genetic sex determination. This makes fish especially suited for studying sex determination from the evolutionary point of view. In several fish groups, different sex determination mechanisms are found in closely related species, and evolution of this process is still ongoing in recent organisms. The medaka (Oryzias latipes) has an XY-XX genetic sex… 
Molecular analysis of the sex-determining region of the platyfish Xiphophorus maculatus.
TLDR
The sex determination region of the platyfish is very instable and frequently undergoes duplications, deletions, and transpositions, which might be linked to the high genetic variability affecting sex determination and other sex-linked traits in Xiphophorus.
A Syntenic Region Conserved from Fish to Mammalian X Chromosome
TLDR
A syntenic segment within this region that is well conserved in several teleosts was shown to be present in mammalian X chromosomes, suggesting a common ancestral origin of vertebrate sex chromosomes.
Genotypic sex determination in teleosts: insights from the testis-determining amhy gene.
TLDR
This study reviewed the molecular process of sex determination in the Patagonian pejerrey Odontesthes hatcheri, an emerging model due to the recent discovery that a Y-chromosome linked, duplicated copy of the anti-Müllerian hormone gene, amhy plays a pivotal role in sex determination.
Sex Chromosome Evolution in Lizards: Independent Origins and Rapid Transitions
TLDR
It is suggested that lizard sex determination may be much more the result of an interplay between sex chromosomes and temperature than previously thought, such that the sex determination mode is influenced by the nature of heterogamety as well as temperature sensitivity and the stage of sex chromosome degeneration.
DMY gene induces male development in genetically female (XX) medaka fish
TLDR
It is demonstrated that a 117-kb genomic DNA fragment that carries DMY is able to induce testis differentiation and subsequent male development in XX (genetically female) medaka and suggested that the functional difference between the X and Y chromosomes in medaka is a single gene.
Sex Chromosome Evolution in a Hermaphrodite
Sex chromosome evolution in a hermaphrodite ancestor starts with the establishment of a sex-determining region (SDR). Over time, sex-specific genes, and/or sexually antagonistic alleles will become
Sex Chromosome Conservation, DMRT1 Phylogeny and Gonad Morphology in Diploid Palearctic Green Toads (Bufo viridis Subgroup)
TLDR
3 cross-amplifying sex-linked microsatellite markers are used to uncover sex determination systems and sex chromosomes in purebred, diploid Palearctic green toads (Bufo viridis subgroup), which had so far only been characterized in laboratory-bred hybrids, and support an XY system in B. viridis and B. variabilis.
Sex Determination in the Squalius alburnoides Complex: An Initial Characterization of Sex Cascade Elements in the Context of a Hybrid Polyploid Genome
TLDR
The contribution of these genes to gonad integrity maintenance and functionality is apparently unaltered in the hybrids, suggesting that no abrupt shifts in gene expression occurred as a result of hybridisation.
Governing Sex Determination in Fish: Regulatory Putsches and Ephemeral Dictators
TLDR
The identification of new sex-determining genes in Oryzias latipes and medaka will shed new light on the exceptional evolutionary instability governing sex determination in fish.
Fish Gonadogenesis. Part I: Genetic and Environmental Mechanisms of Sex Determination
TLDR
This review concentrates on recent research using the tools of molecular biology to broaden the understanding of the different aspects related to fish sex determination, both in model fish species and in species of commercial importance.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 66 REFERENCES
Absence of the Candidate Male Sex-Determining Gene dmrt1b(Y) of Medaka from Other Fish Species
TLDR
It is found that the gene duplication generating dmrt1b(Y) occurred recently during the evolution of the genus Oryzias, which means that it may not be the male-sex determining gene in all fishes.
Variability of genetic sex determination in poeciliid fishes
TLDR
It is proposed that the high plasticity of the sex-determining region might explain the variability of sex determination in Xiphophorus and other poeciliids.
Identification of the sex chromosomes of the medaka, Oryzias latipes, by fluorescence in situ hybridization
In the medaka, Oryzias latipes, which does not have cytologically recognizable sex chromosomes, the sex is genetically determined and the mechanism of sex determination (XX/XY) can be revealed by
A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes
  • I. Nanda, M. Kondo, +9 authors M. Schartl
  • Biology, Medicine
    Proceedings of the National Academy of Sciences of the United States of America
  • 2002
TLDR
It is found that in the fish medaka the Y chromosome-specific region spans only about 280 kb and contains a duplicated copy of the autosomal DMRT1 gene, named D MRT1Y, which is the only functional gene in this chromosome segment and maps precisely to the male sex-determining locus.
Molecular-cytogenetic analysis reveals sequence differences between the sex chromosomes of Oreochromis niloticus: evidence for an early stage of sex-chromosome differentiation
TLDR
It is shown that chromosome microdissection and subsequent amplification by degenerate oligonucleotide-primed PCR (DOP-PCR) can be used to produce in situ hybridization probes to this largest pair of O. niloticus chromosomes, providing further support for the theory that this chromosome pair is related to sex determination and suggests that the sex chromosomes are at a very early stage of divergence.
Cloning of the dmrt1 gene of Xiphophorus maculatus: dmY/dmrt1Y is not the master sex-determining gene in the platyfish.
TLDR
Phylogenetic analysis indicated that the duplication of dmrt1 that led to the formation of dMY/dmrt1Y within the medaka lineage clearly occurred after its divergence from the platyfish lineage, and a dmY/DMRT1Y orthologue generated by this particular event of duplication does not correspond to the master sex-determining gene in the platYfish.
Differences in recombination frequencies during female and male meioses of the sex chromosomes of the medaka, Oryzias latipes.
TLDR
The hypothesis that the heterogeneous sex chromosomes in the medaka were derived from suppression of recombination between autosomal chromosomes is supported.
Common spontaneous sex-reversed XX males of the medaka Oryzias latipes.
TLDR
The screening of strains of Northern and Southern medaka indicated that the candidate male sex-determining gene dmrt1bY may not be necessary for male development in every case, but that its function can be taken over by so far unidentified autosomal modifiers.
DMY is a Y-specific DM-domain gene required for male development in the medaka fish
TLDR
Rec recombinant breakpoint analysis is used to restrict the sex-determining region in medaka fish to a 530-kilobase stretch of the Y chromosome, and it is suggested that thesex-specific DMY is required for testicular development and is a prime candidate for the medaka sex-Determining gene.
Sex determination and sex differentiation in fish: an overview of genetic, physiological, and environmental influences
TLDR
The lability of sex-determination systems in fish makes some species sensitive to environmental pollutants capable of mimicking or disrupting sex hormone actions, and such observations provide important insight into potential impacts from endocrine disruptors, and can provide useful monitoring tools for impacts on aquatic environments.
...
1
2
3
4
5
...