A comparative study on the effects of tetracyclines and lithium on the cyclic amp second messenger system in rat brain

@article{Mrk1995ACS,
  title={A comparative study on the effects of tetracyclines and lithium on the cyclic amp second messenger system in rat brain},
  author={Arne M{\o}rk and Arne Geisler},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={1995},
  volume={19},
  pages={157-169}
}
  • A. Mørk, A. Geisler
  • Published 31 January 1995
  • Biology, Chemistry
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
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10 Citations
Background Citations
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Results Citations
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10 Citations

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Citation Type

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References

SHOWING 1-10 OF 45 REFERENCES
Effects of lithium in vitro and ex vivo on components of the adenylate cyclase system in membranes from the cerebral cortex of the rat
Effects of treatment with a lithium-imipramine combination on components of adenylate cyclase in the cerebral cortex of the rat
Effects of lithium and desimipramine on second messenger responses in rat hippocampus: relation to G protein effects
Effects of lithium ex vivo on the GTP-mediated inhibition of calcium-stimulated adenylate cyclase activity in rat brain.
Inhibition by antibiotic tetracyclines of rat cortical noradrenergic adenylate cyclase and amphetamine-induced hyperactivity
Effects of lithium on calmodulin-stimulated adenylate cyclase activity in cortical membranes from rat brain.
TLDR
The present results suggest that lithium might influence the interaction of calmodulin with the enzyme and/or interfere with the divalent cation site(s) on the adenylate cyclase system.
Calmodulin-dependent adenylate cyclase activity in rat cerebral cortex: effects of divalent cations, forskolin and isoprenaline.
TLDR
It is demonstrated that Ca2+ -CaM potentiates beta-adrenergic adenylate cyclase activity and thus is able to modulate neurotransmitter stimulation in cortex and thus can be restored by addition of exogenous CaM.
Transfected Go1 alpha inhibits the calcium dependence of beta-adrenergic stimulated cAMP accumulation in C6 glioma cells.
Effects of lithium and rolipram enantiomers on locomotor activity in inbred mice.
  • D. Smith
  • Psychology, Biology
    Pharmacology & toxicology
  • 1990
TLDR
The behavioural findings are consistent with the opposite pharmacological effects of lithium and rolipram on cAMP, and support the notion that cAMP availability in brain may play a role in behavioural effects of the drugs.
Synergistic activation of brain adenylate cyclase by calmodulin, and either GTP or catecholamines including dopamine
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