A comparative study of thiamine with metformin on fasting blood glucose of diabetic albino rats

@article{Choudhury2016ACS,
  title={A comparative study of thiamine with metformin on fasting blood glucose of diabetic albino rats},
  author={S. Choudhury and Bhulan Prasad Loc and Rati Ranjan Debbarma and Arijit Das},
  journal={International journal of basic and clinical pharmacology},
  year={2016},
  volume={5},
  pages={1539-1543}
}
Background: Thiamine is a member of the vitamin B family. Thiamine is necessary for normal insulin synthesis and secretion. In diabetes thiamine and its derivative benfotiamine showed promising results in prevention of microvascular complications. Some experimental and clinical studies have shown the antihyperglycaemic effect of thiamine. This study compared the antihyperglycaemic effect of thiamine with metformin in streptozotocin-nicotinamide induced diabetic albino rats. Methods: 24 albino… Expand

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