A comparative study of the regulation of cytochrome P-450 and glutathione transferase gene expression in rat liver.

Abstract

A cDNA clone for the Ya subunit of glutathione transferase from rat liver was constructed in E. coli. The clone hybridized to Ya and Yc subunit messenger RNAs. On the basis of experiments involving cell-free translation and hybridization to the cloned probe, it was shown that prototype inducers of cytochrome P-450 such as phenobarbitone and 3… (More)

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@article{Francis1986ACS, title={A comparative study of the regulation of cytochrome P-450 and glutathione transferase gene expression in rat liver.}, author={Vishal Francis and V I Dwarki and Govindarajan Padmanaban}, journal={Nucleic acids research}, year={1986}, volume={14 6}, pages={2497-510} }