A comparative study of the effects of quercetin and its glucuronide and sulfate metabolites on human neutrophil function in vitro.

@article{Suri2008ACS,
  title={A comparative study of the effects of quercetin and its glucuronide and sulfate metabolites on human neutrophil function in vitro.},
  author={Sunita Suri and Moira A Taylor and Anne Verity and Sandra Tribolo and Paul W. Needs and Paul Anthony Kroon and David A. Hughes and Vincent G Wilson},
  journal={Biochemical pharmacology},
  year={2008},
  volume={76 5},
  pages={645-53}
}
Exposure of neutrophils to either lipopolysaccharide (LPS) or N-formyl-methionyl-leucyl-phenylalanine (fMLP) is associated with changes in the expression of cell adhesion molecules and elevation of intracellular calcium ions. Although dietary flavonoids are reported to possess anti-inflammatory properties, little is known regarding the effect of their metabolites. We have investigated the effects of quercetin and its major metabolites on LPS and fMLP-stimulated human neutrophils using… CONTINUE READING

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