A comparative study of the effects of carbamazepine and the NMDA receptor antagonist remacemide on road tracking and car-following performance in actual traffic

@article{Ramaekers2002ACS,
  title={A comparative study of the effects of carbamazepine and the NMDA receptor antagonist remacemide on road tracking and car-following performance in actual traffic},
  author={Jan Ramaekers and C G Lamers and Frans R J Verhey and Nienke Muntjewerff and E. G. Mobbs and Nicole C Sanders and Joseph A. Lewis and J Andrew Lockton},
  journal={Psychopharmacology},
  year={2002},
  volume={159},
  pages={203-210}
}
Rationale: Antiepileptic drugs are known to produce side effects which may impair driving performance. Performance effects, however, may differ substantially between individual antiepileptic drugs. Objective: To compare the effects of carbamazepine, remacemide, and placebo on actual driving performance during a 12-day incremental dosing regimen. Methods: Twenty-two healthy volunteers participated in a three-way, double-blind, cross-over driving study. Treatment effects were assessed in two… CONTINUE READING

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