A comparative study of tea‐tree oil versus benzoylperoxide in the treatment of acne

  title={A comparative study of tea‐tree oil versus benzoylperoxide in the treatment of acne},
  author={I B Bassett and Ross St C Barnetson and D Pannowitz},
  journal={Medical Journal of Australia},
Tea‐tree oil (an essential oil of the Australian native tree Melaleuca alter‐ nifolia) has long been regarded as a useful topical antiseptic agent in Australia and has been shown to have a variety of antimicrobial activities; however, only anecdotal evidence exists for its efficacy in the treatment of various skin conditions. We have performed a single‐blind, randomised clinical trial on 124 patients to evaluate the efficacy and skin tolerance of 5% tea‐tree oil gel in the treatment of mild to… 
Tea tree oil cream appears to reduce the symptomatology of tinea pedis as effectively as tolnaftate 1% but is no more effective than placebo in achieving a mycological cure.
A review of applications of tea tree oil in dermatology
This review opens up new horizons for dermatologists in the use of this herbal agent in the treatment of acne vulgaris, seborrheic dermatitis, and chronic gingivitis.
Topical antimicrobial therapy with tea tree oil: fact or fantasy
Based on the published data, tea tree oil may prove to be a very useful topical antimicrobial and there is a role for infection control practitioners in the validation of its use in clinical practice.
Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Evaluating the anti-acne efficacy of a new cream based on three natural extracts, comparing it to erythromycin cream and placebo found the PTAC formulation was better than ERC in reducing erythema scars, acne severity index, and total lesion count.
Treatment of dandruff with 5% tea tree oil shampoo.
Five percent tea tree oil appears to effective and well tolerated in the treatment of dandruff.
Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical Trial
5% TTO gel is effective in the treatment of mild to moderate facial seborrheic dermatitis and allergic side - effects were seen in neither group.
The antimicrobial activity of tea tree oil
The antimicrobial activity of a number of commercially available samples of tea tree oil was compared, and Pseudomonas aeruginosa was uniformly resistant to all brands of oil.
Tea Tree Oil: A Systematic Review of Randomized Clinical Trials
It is concluded that, so far, there is no compelling evidence to show that TTO is efficacious in any dermatological condition, however, in view of promising findings, TTO deserves to be investigated more closely.
Tea tree oil allergy: What is the offending agent? Report of three cases of tea tree oil allergy and review of the literature
It is important that physicians are aware of the potential adverse effects of these products and identification of the allergenic ingredients in lea tree oil may assist the growing industry to produce safer products.


Gas chromatographic quality control for oil of Melaleuca terpinen-4-ol type (Australian tea tree)
Detailed GC and GC-MS analyses of oil of Melaleuca have identified several constituents not previously reported from Melaleuca alternifolia and clarified some earlier assignments. The range, mean,
Acne vulgaris: pathogenesis and treatment.
Colposcopy will reduce but not eliminate the need for cone biopsy in women of child-bearing age and patients who conceive after an operation on the cervix should be assessed by the obstetrician as early as possible.
Cytotoxic activity of Propionibacterium acnes and other skin organisms
Culture supernatants from four species of skin micro‐organisms were tested against VERO (monkey kidney cells) and skin fibroblasts for cytotoxic activity and Staphylococcus epidermidis was devoid of cytotoxicity activity whether grown in the presence of glucose or not.
Inflammation in acne vulgaris: leukocyte attraction and cytotoxicity by comedonal material.
The attraction and killing of leukocytes by comedonal components may be the mechanisms for the initiation or the enhancement (or both) of inflammation in acne vulgaris.
The assessment of acne vulgaris—the Leeds technique
Two simple, reproducible scoring systems for assessing acne severity are described, and the technical problems which could invalidate either technique are emphasized.
Australian tea-tree oil - a natural antiseptic
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