A comparative study of pharmacodynamics and bioavailability of 2 different desmopressin nasal sprays.

@article{Eller1998ACS,
  title={A comparative study of pharmacodynamics and bioavailability of 2 different desmopressin nasal sprays.},
  author={Nanna Eller and Christian J. Kollenz and Gerhart Hitzenberger},
  journal={International journal of clinical pharmacology and therapeutics},
  year={1998},
  volume={36 3},
  pages={139-45}
}
The antidiuretic effect and pharmacokinetics were investigated in 16 healthy, male overhydrated volunteers after intranasal administration of 20 microg desmopressin. The antidiuretic activity was measured by determination of urine osmolality and diuresis every 15 minutes over a period of 8 hours. Both study preparations were equally effective regarding a… CONTINUE READING