A comparative study of gastrointestinal bleeding during administration of ketoprofen and naproxen.


The gastrointestinal blood losses arising after ketoprofen and naproxen therapy were studied in 12 male volunteers. A 51Cr-technique was used and the study was carried out using a double-blind crossover design. The median daily blood losses were 3.3 and 1.2 ml after ketoprofen and naproxen, respectively. Both preparations caused significantly increased… (More)


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