A comparative study of combination chemotherapy versus marrow transplant in first remission in adult acute lymphoblastic leukaemia.

@article{Proctor1988ACS,
  title={A comparative study of combination chemotherapy versus marrow transplant in first remission in adult acute lymphoblastic leukaemia.},
  author={Stephen John Proctor and Peter S. Hamilton and P L Taylor and Patrick H. Carey and S. M. Hargrave and Richard G. Evans and Geoffrey P. Summerfield and R C Finney and Philippa Saunders and Donald Goff},
  journal={British journal of haematology},
  year={1988},
  volume={69 1},
  pages={35-9}
}
The results of conventional chemotherapy in adult acute lymphoblastic leukaemia (ALL) have not improved substantially in recent years. The present study is based on a flexible policy of marrow transplantation (allograft and autograft without marrow purging) in first remission compared with a group treated with standard maintenance therapy after a common induction sequence. The actuarial disease free survival (DFS) and actuarial overall survival (OS) at 3 years for autologous marrow grafted… CONTINUE READING

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