A comparative study of combination chemotherapy versus marrow transplant in first remission in adult acute lymphoblastic leukaemia.

@article{Proctor1988ACS,
  title={A comparative study of combination chemotherapy versus marrow transplant in first remission in adult acute lymphoblastic leukaemia.},
  author={StephenJ. Proctor and Peter S. Hamilton and Pauline B. Taylor and Patrick H. Carey and S. M. Hargrave and Richard G. Evans and Geoffrey P. Summerfield and Ruth Finney and Philippa Saunders and Donald H. Goff},
  journal={British journal of haematology},
  year={1988},
  volume={69 1},
  pages={
          35-9
        }
}
The results of conventional chemotherapy in adult acute lymphoblastic leukaemia (ALL) have not improved substantially in recent years. The present study is based on a flexible policy of marrow transplantation (allograft and autograft without marrow purging) in first remission compared with a group treated with standard maintenance therapy after a common induction sequence. The actuarial disease free survival (DFS) and actuarial overall survival (OS) at 3 years for autologous marrow grafted… CONTINUE READING
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