A comparative study of Merkel cell, BK and JC polyomavirus infections in renal transplant recipients and healthy subjects.

@article{Husseiny2010ACS,
  title={A comparative study of Merkel cell, BK and JC polyomavirus infections in renal transplant recipients and healthy subjects.},
  author={Mohamed I Husseiny and Bishoy Anastasi and Jennifer Singer and Simon F Lacey},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2010},
  volume={49 2},
  pages={137-40}
}
BACKGROUND Merkel cell carcinoma (MCC) is a rare skin cancer associated with immunosuppression and the integration of Merkel cell polyomavirus (MCPyV) DNA into the tumor cell genome. Little is known about the natural history of MCPyV infection. OBJECTIVES To investigate the presence of MCPyV, BK and JC polyomaviruses in serum and urine from immunosuppressed kidney transplant patients (KTx) and a control group of normal volunteers. STUDY DESIGN Quantitative real-time PCR (q-PCR) was used to… CONTINUE READING
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