A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

  title={A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.},
  author={Stephen S. Lim and Theo Vos and Abraham D. Flaxman and Goodarz Danaei and Kenji Shibuya and Heather Adair-Rohani and Markus Amann and Hugh Ross Anderson and Kathryn G Andrews and Martin J. Aryee and Charles Atkinson and Loraine J Bacchus and Adil N Bahalim and K. S. Balakrishnan and John R Balmes and Suzanne Lyn Barker-Collo and Amanda J. Baxter and Michelle L. Bell and Jed Daniel Blore and Fiona M. Blyth and Carissa Bonner and Guilherme Borges and Rupert R A Bourne and Michel Boussinesq and Michael Brauer and Peter Brooks and Nigel G. Bruce and Bert A Brunekreef and Claire Bryan-Hancock and Chiara Bucello and Rachelle Buchbinder and Fiona C Bull and Richard T. Burnett and Tim E. Byers and Bianca Calabria and Jonathan Carapetis and Emily Carnahan and Zoe Chafe and Fiona Charlson and Honglei Chen and Jian Shen Chen and Andrew T. A. Cheng and Jennifer Christine Child and Aaron Cohen and Katherine Ellicott Colson and Benjamin C. Cowie and Sefton Darby and Susan M. Darling and Adrian Davis and Louisa Degenhardt and Frank Dentener and Don C Des Jarlais and Karen M Devries and Mukesh Dherani and Eric L. Ding and E. Ray Dorsey and Tim Driscoll and Karen Edmond and Suad Eltahir Ali and Rebecca E. Engell and Patricia J. Erwin and Saman Fahimi and Gail Falder and Farshad Farzadfar and Alize J. Ferrari and Mariel M. Finucane and Seth Flaxman and Francis Gerry R. Fowkes and Greg D. Freedman and Michael K Freeman and Emmanuela Gakidou and Santu Ghosh and Edward L. Giovannucci and Gerhard Gmel and Kathryn F. Graham and Rebecca Grainger and Bridget F. Grant and D Gunnell and H. Rafael Guti{\'e}rrez and W. Darrin Hall and Hans W Hoek and Anthony R. Hogan and Howard Dean Hosgood and Damian Hoy and Howard Hu and Bryan J. Hubbell and Sally J Hutchings and Sydney E Ibeanusi and Gemma Jacklyn and Rashmi Jasrasaria and Jost Bruno Jonas and Haidong Kan and J. A. Kanis and Nicholas J. Kassebaum and Norito Kawakami and Young Ho Khang and Shahab Khatibzadeh and Jon-Paul Khoo and Cindy Kok and Francine Laden and Ratilal Lalloo and Qing Lan and Tim Lathlean and Janet L Leasher and James Leigh and Yang Li and John Kent Lin and Steven E. Lipshultz and Stephanie J London and Rafael Lozano and Yuan Lu and Joelle Y T Mak and Reza Malekzadeh and Leslie Mallinger and Wagner Marcenes and Lyn March and Robin Marks and Randall Martin and Paul McGale and John McGrath and Sumi Mehta and George A. Mensah and Tony Raymond Merriman and Renata Micha and Catherine M. Michaud and Vinod Mishra and Khayriyyah Mohd Hanafiah and Ali A Mokdad and Lidia Morawska and Dariush Mozaffarian and Tasha B. Murphy and Mohsen Naghavi and Bruce Neal and Paul Kurt Nelson and Joan Miquel Nolla and Rosana E Norman and Casey Olives and Saad B Omer and Jessica Joan Orchard and Richard Osborne and Bart Ostro and Andrew Page and Kiran Dev Pandey and Charles D H Parry and Erin Passmore and Jayadeep Patra and Neil Pearce and Pamela M Pelizzari and Max Petzold and Michael Phillips and Daniel P Pope and Christina Pope and John W Powles and Mayuree Rao and Homie Razavi and Eva Rehfuess and J{\"u}rgen Rehm and Beate Ritz and Frederick P. Rivara and Thomas Roberts and Carolyn Robinson and Jose Adolfo Rodriguez-Portales and Isabelle Romieu and Robin Room and Lisa C Rosenfeld and Ananya Roy and Lesley Rushton and Joshua A Salomon and Uchechukwu Sampson and L{\'i}dia S{\`a}nchez-Riera and Ella Sanman and Amir Sapkota and Soraya Seedat and Peilin Shi and Kevin D Shield and Rupak Shivakoti and Gitanjali M. Singh and David A. Sleet and Emma Smith and Kirk R. Smith and Nicolas J C Stapelberg and Kyle N. Steenland and Heidi Stoeckl and Lars Stovner and Kurt Straif and Lahn D Straney and George Thurston and Jimmy H Tran and Rita van Dingenen and Aaron van Donkelaar and Jacob Lennert Veerman and Lakshmi Vijayakumar and Robert G. Weintraub and Myrna M. Weissman and Richard A. White and Harvey Whiteford and Steven Todd Wiersma and James Dean Wilkinson and Hywel C Williams and Warwick Williams and N. Wilson and Anthony D. Woolf and Paul Yip and Jan M Zielinski and Alan D Lopez and C. J. Murray and Majid Ezzati and Mohammad A. Almazroa and Ziad Ahmed Memish},
  volume={380 9859},
BACKGROUND Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a disease-by-disease analysis. No complete revision of global disease burden caused by risk factors has been done since a comparative risk assessment in 2000, and no previous analysis has assessed changes in burden attributable to risk factors over time. METHODS We estimated deaths and disability-adjusted life years (DALYs; sum of… CONTINUE READING
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