A comparative review of aging and B cell function in mice and humans.

Abstract

Immune system function declines with age. Here we review and compare age-associated changes in murine and human B cell pools and humoral immune responses. We summarize changes in B cell generation and homeostasis, as well as notable changes at the subcellular level; then discuss how these changes help to explain alterations in immune responses across the… (More)
DOI: 10.1016/j.coi.2013.07.006

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