A comparative performance test of standard, medium- and high-throughput comet assays.

@article{Azqueta2013ACP,
  title={A comparative performance test of standard, medium- and high-throughput comet assays.},
  author={Amaya Azqueta and Kristine Bjerve Gutzkow and Catherine C Priestley and Silja Meier and Joanne S Walker and Gunnar Brunborg and Andrew R Collins},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2013},
  volume={27 2},
  pages={768-73}
}
A serious limitation of the conventional comet assay (single cell gel electrophoresis) is the restriction on the number of samples that can be processed in one experiment, imposed by the size of the electrophoresis platform. One approach to increasing throughput is to reduce the size of gels. We here compare the conventional system of two large gels on a microscope slide, with two recent developments, namely 12 minigels per slide, and a format with 96 minigels on GelBond® film. We used cells… CONTINUE READING

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