A comparative kinetic study of thiamphenicol in pre-ruminant lambs and calves.

@article{Mengozzi2002ACK,
  title={A comparative kinetic study of thiamphenicol in pre-ruminant lambs and calves.},
  author={Grazia Mengozzi and Luigi Intorre and Simone Bertini and Mario Giorgi and Pier Lorenzo Secchiari and G. Guidi Soldani},
  journal={Research in veterinary science},
  year={2002},
  volume={73 3},
  pages={
          291-5
        }
}
Eight healthy Holstein-Friesian calves and 8 Massese lambs of either sex (10-15-days old) were used to evaluate the pharmacokinetics of thiamphenicol after intravenous (i.v.) and oral (p.o.) administration (30 mg/kg). Plasma concentrations of thiamphenicol were determined by high-performance liquid chromatography on blood samples collected over 24h following treatment. Pharmacokinetic variables of the drug were calculated for both species and after both administration routes. After intravenous… CONTINUE READING
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