A comparative genomic analysis of two distant diptera, the fruit fly, Drosophila melanogaster, and the malaria mosquito, Anopheles gambiae.

@article{Bolshakov2002ACG,
  title={A comparative genomic analysis of two distant diptera, the fruit fly, Drosophila melanogaster, and the malaria mosquito, Anopheles gambiae.},
  author={Viacheslav N. Bolshakov and Pantelis Topalis and Claudia Blass and Elena Kokoza and Alessandra della Torre and Fotis C. Kafatos and Christos Louis},
  journal={Genome research},
  year={2002},
  volume={12 1},
  pages={57-66}
}
Genome evolution entails changes in the DNA sequence of genes and intergenic regions, changes in gene numbers, and also changes in gene order along the chromosomes. Genes are reshuffled by chromosomal rearrangements such as deletions/insertions, inversions, translocations, and transpositions. Here we report a comparative study of genome organization in the main African malaria vector, Anopheles gambiae, relative to the recently determined sequence of the Drosophila melanogaster genome. The… CONTINUE READING

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