A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences

@article{Shaaban2011ACB,
  title={A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences},
  author={Mohammed Q. Shaaban and Graham Roy Ball and Rebecca A. Brannan and G{\'a}bor Cserni and Anna Di Benedetto and A. J. Dent and Laura Fulford and Helen Honarpisheh and L Wilson Jordan and Jennifer L. Jones and R. L. Kanthan and Loaie Maraqa and Maria Litwiniuk and Marcella Mottolese and Steven W. Pollock and Elena Provenzano and Philip Roy Quinlan and Georgina Reall and Sami Shousha and Mark Stephens and Eldo Thomas Verghese and Rosemary A. C. Walker and Andrew M. Hanby and Valerie Speirs},
  journal={Breast Cancer Research and Treatment},
  year={2011},
  volume={133},
  pages={949-958}
}
Male breast cancer remains understudied despite evidence of rising incidence. Using a co-ordinated multi-centre approach, we present the first large scale biomarker study to define and compare hormone receptor profiles and survival between male and female invasive breast cancer. We defined and compared hormone receptor profiles and survival between 251 male and 263 female breast cancers matched for grade, age, and lymph node status. Tissue microarrays were immunostained for ERα, ERβ1, -2, -5… CONTINUE READING

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