A comparative analysis of the intestinal metagenomes present in guinea pigs (Cavia porcellus) and humans (Homo sapiens)

@inproceedings{Hildebrand2012ACA,
  title={A comparative analysis of the intestinal metagenomes present in guinea pigs (Cavia porcellus) and humans (Homo sapiens)},
  author={Falk Hildebrand and Tine Ebersbach and Henrik Bj{\o}rn Nielsen and Xiaoping Li and Si B. Sonne and Marcelo Bertalan and Peter Stoykov Dimitrov and Lise Madsen and Junjie Jia Guowei Qin and Jun Wang and Jeroen Raes and Karsten Kristiansen and Tine Rask Licht},
  booktitle={BMC Genomics},
  year={2012}
}
Guinea pig (Cavia porcellus) is an important model for human intestinal research. We have characterized the faecal microbiota of 60 guinea pigs using Illumina shotgun metagenomics, and used this data to compile a gene catalogue of its prevalent microbiota. Subsequently, we compared the guinea pig microbiome to existing human gut metagenome data from the MetaHIT project. We found that the bacterial richness obtained for human samples was lower than for guinea pig samples. The intestinal… CONTINUE READING
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