A comparative analysis of molecular mechanisms for blocking polyspermy: identification of a lectin-ligand binding reaction in mammalian eggs.

  • Jerry L. Hedrick
  • Published 2007 in Society of Reproduction and Fertility supplement


Fertilization is a critically important event to the creation of a new individual organism and to the propagation of a species. Evolutionarily conserved cellular and molecular mechanisms exist to modify the glycoproteins composing the egg extracellular matrix at fertilization. These matrix modifications regulate the cellular interactions of sperm and egg… (More)


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