A common sequence motif near nonhomologous recombination breakpoints involving Ig sequences.

Abstract

Analysis of nonhomologous recombination events at the Ig loci revealed that a four base sequence, 5'-CCAG-3', or its complement, 5'-CTGG-3', is present within seven nucleotides in 12 of the 13 examined recombination breakpoints. Statistical analysis of the data indicates that this occurrence has a probability of less than 10(-5) of occurring by chance. This… (More)

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Cite this paper

@article{Chou1993ACS, title={A common sequence motif near nonhomologous recombination breakpoints involving Ig sequences.}, author={C. L. Chou and Sherie L. Morrison}, journal={Journal of immunology}, year={1993}, volume={150 12}, pages={5350-60} }