A common regulatory region shared by divergently transcribed genes of the Escherichia coli SOS system

@article{Brandsma1983ACR,
  title={A common regulatory region shared by divergently transcribed genes of the Escherichia coli SOS system},
  author={Jourica A. Brandsma and D. Bosch and Claude Backendorf and P. van de Putte},
  journal={Nature},
  year={1983},
  volume={305},
  pages={243-245}
}
The Escherichia coli single-stranded DNA binding protein (SSB) is implicated in DNA replication, recombination and repair1. On the chromosome, the ssb gene is located adjacent to the excision repair gene uvrA, but the two genes are transcribed in opposite directions2. uvrA has been shown to be part of the E. coli SOS system by introducing Mud(Ap, lac) insertions distal to the regulatory region of the gene in the chromosome3. Recent investigations suggest that SSB is also involved in the SOS… CONTINUE READING

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