A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft

@inproceedings{Baron2015ACG,
  title={A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft},
  author={Daniel Baron and G{\'e}rard Ramstein and M{\'e}lanie Chesneau and Yann Echasseriau and Annaick Pallier and Chlo{\'e} Paul and Nicolas Degauque and Maria P Hernandez-Fuentes and Alberto Sanchez-Fueyo and Kenneth A. Newell and Magali Giral and Jean Paul Soulillou and R{\'e}mi Houlgatte and Sophie Brouard},
  booktitle={Kidney international},
  year={2015}
}
Patients tolerant to a kidney graft display a specific blood cell transcriptional pattern but results from five different studies were inconsistent, raising the question of relevance for future clinical application. To resolve this, we sought to identify a common gene signature, specific functional and cellular components, and discriminating biomarkers for tolerance following kidney transplantation. A meta-analysis of studies identified a robust gene signature involving proliferation of B and… CONTINUE READING
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