A common function for polyoma virus large-T and papillomavirus E1 proteins?

@article{Clertant1984ACF,
  title={A common function for polyoma virus large-T and papillomavirus E1 proteins?},
  author={Philippe Clertant and Isabelle Seif},
  journal={Nature},
  year={1984},
  volume={311},
  pages={276-279}
}
Nucleotide sequencing has revealed a common genetic organization for three papillomaviruses: BPV-1 (bovine papillomavirus type 1), HPV-1 (human papillomavirus type 1a) and HPV-6 (human papillomavirus type 6b)1–4. Several open reading frames, corresponding to as yet uncharacterized proteins, were observed in these genomes in the region that is required for oncogenic transformation by BPV-1 and for plasmidial maintenance of its genome5. The longest of these frames, E1, is also the most conserved… CONTINUE READING