A combined hepatocellular/cholangiocellular carcinoma with sarcomatoid features.

@article{Papotti1997ACH,
  title={A combined hepatocellular/cholangiocellular carcinoma with sarcomatoid features.},
  author={Mauro Papotti and Daniela Sambataro and Pierenrico Marchesa and F. de Toro Negro},
  journal={Liver},
  year={1997},
  volume={17 1},
  pages={47-52}
}
A case of primary liver cancer showing combined hepatocellular and cholangiocellular features and an associated pseudosarcomatous (schwannomatous) component is presented. Histologically, compact microtrabecular and glandular patterns in a dense fibrous stroma were recognized. The latter showed transition towards spindle cell sarcomatous growth in several areas of both the primary and the lymph-node metastasis. Glandular areas expressed acidic mucins and AE1-reactive keratins; albumin mRNA was… CONTINUE READING