A combined dataset of human cerebrospinal fluid proteins identified by multi-dimensional chromatography and tandem mass spectrometry.

@article{Pan2007ACD,
  title={A combined dataset of human cerebrospinal fluid proteins identified by multi-dimensional chromatography and tandem mass spectrometry.},
  author={Sheng Pan and David J. Zhu and Joseph F Quinn and E. R. Peskind and Thomas J. Montine and Biaoyang Lin and David R. Goodlett and Greg N Taylor and Jimmy Eng and Jing Zhang},
  journal={Proteomics},
  year={2007},
  volume={7 3},
  pages={
          469-73
        }
}
Human cerebrospinal fluid (CSF) is an important source for studying protein biomarkers of age-related neurodegenerative diseases. Before characterizing biomarkers unique to each disease, it is necessary to categorize CSF proteins systematically and extensively. However, the enormous complexity, great dynamic range of protein concentrations, and tremendous protein heterogeneity due to post-translational modification of CSF create significant challenges to the existing proteomics technologies for… CONTINUE READING
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