A combined computational and experimental study of the hydrogen-bonded dimers of xanthine and hypoxanthine.

@article{Hupp2005ACC,
  title={A combined computational and experimental study of the hydrogen-bonded dimers of xanthine and hypoxanthine.},
  author={Thomas Hupp and Christian Sturm and Eline M Bas{\'i}lio Janke and Montserrat P{\'e}rez Cabre and Klaus Weisz and Bernd Engels},
  journal={The journal of physical chemistry. A},
  year={2005},
  volume={109 8},
  pages={1703-12}
}
In addition to uracil, the noncanonical nucleobases xanthine and hypoxanthine are important lesions that are formed from the canonical bases when a cell is under oxidative stress. It is known that they lead to point mutations; however, more detailed information about their ability to form hydrogen-bonded complexes is not available. In the present paper such information is obtained by a combined experimental and theoretical approach. Accurate association constants of xanthosine and inosine… CONTINUE READING

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…