A combined [11C]diprenorphine PET study and fMRI study of acupuncture analgesia.

  title={A combined [11C]diprenorphine PET study and fMRI study of acupuncture analgesia.},
  author={Darin D. Dougherty and Jian Kong and Megan Webb and Ali Akbarpour Bonab and Alan J. Fischman and Randy L. Gollub},
  journal={Behavioural brain research},
  volume={193 1},
Functional neuroimaging studies suggest that a lateral network in the brain is associated with the sensory aspects of pain perception while a medial network is associated with affective aspects. The highest concentration of opioid receptors is in the medial network. There is significant evidence that endogenous opioids are central to the experience of pain and analgesia. We applied an integrative multimodal imaging approach during acupuncture. We found functional magnetic resonance imaging… CONTINUE READING