A combinatorial approach to the synthesis of cystine based organogelators.

Abstract

A solid-phase approach was used to prepare 20 cystine amide derivatives with disulfide bond formation resulting from an intra-site reaction between neighbouring cysteine residues. Library members were screened as potential organogelators in a range of solvent mixtures and resulted in the identification of a potent gelator able to rigidify water/DMSO mixtures at concentrations as low as 1.3 mM.

Cite this paper

@article{Matteucci2004ACA, title={A combinatorial approach to the synthesis of cystine based organogelators.}, author={Mizio Matteucci and Gurdip Bhalay and Mark Bradley}, journal={Journal of peptide science : an official publication of the European Peptide Society}, year={2004}, volume={10 6}, pages={318-25} }