A combination therapy protocol of plasmapheresis, intravenous immunoglobulins and betamethasone to treat anti-Ro/La-related congenital atrioventricular block. A case series and review of the literature.

@article{Ruffatti2013ACT,
  title={A combination therapy protocol of plasmapheresis, intravenous immunoglobulins and betamethasone to treat anti-Ro/La-related congenital atrioventricular block. A case series and review of the literature.},
  author={Amelia Ruffatti and Piero Marson and Giorgio Svaluto-Moreolo and Luca Marozio and Maria Tibaldi and Maria Favaro and Antonia Calligaro and Chiara Grava and Ariela Hoxha and Vittorio Pengo and Leonardo Punzi},
  journal={Autoimmunity reviews},
  year={2013},
  volume={12 7},
  pages={768-73}
}
OBJECTIVES The aim of this report was to evaluate the efficacy and safety of a combined treatment protocol used to treat 2nd and 3rd degree anti-Ro/La-related congenital atrioventricular block (CAVB). METHODS Six consecutive women diagnosed with 2nd degree (three cases) or 3rd degree block (three cases) between 2009 and 2011 referred to our outpatient clinic underwent a combination therapy protocol composed of weekly plasmapheresis, fortnightly 1g/kg intravenous immunoglobulins (IVIG) and… CONTINUE READING