A colorimetric and fluorescent probe for detecting intracellular biothiols.


A new rapid and highly sensitive coumarin-based probe (probe 1) has been designed and synthesized for detecting intracellular thiols. Probe 1 was prepared by a 4-step procedure as a latent fluorescence probe to achieve high sensitivity and fluorescence turn-on response toward cysteine and homocysteine over GSH and other various natural amino acids under… (More)
DOI: 10.1016/j.bios.2016.04.098