A colorful origin for the genetic code: Information theory, statistical mechanics and the emergence of molecular codes

@article{Tlusty2010ACO,
  title={A colorful origin for the genetic code: Information theory, statistical mechanics and the emergence of molecular codes},
  author={T. Tlusty},
  journal={Physics of life reviews},
  year={2010},
  volume={7 3},
  pages={
          362-76
        }
}
  • T. Tlusty
  • Published 2010
  • Mathematics, Computer Science, Medicine, Biology, Physics
  • Physics of life reviews
The genetic code maps the sixty-four nucleotide triplets (codons) to twenty amino-acids. While the biochemical details of this code were unraveled long ago, its origin is still obscure. We review information-theoretic approaches to the problem of the code's origin and discuss the results of a recent work that treats the code in terms of an evolving, error-prone information channel. Our model - which utilizes the rate-distortion theory of noisy communication channels - suggests that the genetic… Expand
50 Citations

Paper Mentions

Blog Post
The information capacity of the genetic code: Is the natural code optimal?
The non-power model of the genetic code: a paradigm for interpreting genomic information
  • D. Gonzalez, S. Giannerini, R. Rosa
  • Mathematics, Medicine
  • Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
  • 2016
Origin and Evolution of the Universal Genetic Code.
Does the Genetic Code Have A Eukaryotic Origin?
  • Z. Zhang, J. Yu
  • Biology, Computer Science
  • Genom. Proteom. Bioinform.
  • 2013
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 123 REFERENCES
A model for the emergence of the genetic code as a transition in a noisy information channel
  • T. Tlusty
  • Biology, Computer Science
  • Journal of theoretical biology
  • 2007
The physical language of molecular codes: A rate-distortion approach to the evolution and emergence of biological codes
  • T. Tlusty
  • Computer Science, Biology
  • 2009 43rd Annual Conference on Information Sciences and Systems
  • 2009
On the Evolution of Redundancy in Genetic Codes
Coevolution theory of the genetic code at age thirty.
  • J. Wong
  • Biology, Medicine
  • BioEssays : news and reviews in molecular, cellular and developmental biology
  • 2005
The Coevolution of Genes and Genetic Codes: Crick’s Frozen Accident Revisited
No accident: genetic codes freeze in error-correcting patterns of the standard genetic code.
  • D. Ardell, G. Sella
  • Biology, Medicine
  • Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 2002
The Impact of Message Mutation on the Fitness of a Genetic Code
Early fixation of an optimal genetic code.
The Genetic Code Is One in a Million
...
1
2
3
4
5
...