A colony-stimulating factor for neutrophil granulocytes: A marked increase of its production by the addition of sodium butyrate and lipopolysaccharide in serum-free culture of RSP-2 · P3 Cells

@inproceedings{Tsuneoka1985ACF,
  title={A colony-stimulating factor for neutrophil granulocytes: A marked increase of its production by the addition of sodium butyrate and lipopolysaccharide in serum-free culture of RSP-2 · P3 Cells},
  author={Kazuko Tsuneoka and Mikio Shikita},
  year={1985}
}
Sodium butyrate, lithium acetate, and hydroxyurea given to serum-free culture of RSP-2 · P3 cells notably reduced the rate of cell proliferation but markedly enhanced the production of such a colony-stimulating factor (CSF) as one that stimulated predominantly neutrophilic granulocyte colony formation in mouse bone marrow cell cultures (Tsuneoka and Shikita, 1984). On the other hand, the production of macrophage CSF was not increased in the butyrate-treated RSP-2 · 3 cells. Butyrate also failed… CONTINUE READING