A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane.

@article{Uemura2014ACO,
  title={A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane.},
  author={Takefumi Uemura and Masaya Yamamoto and Ai Kametaka and Yu-shin Sou and Atsuko Yabashi and Akane Yamada and Hiromichi Annoh and Satoshi Kametaka and M. Asaliaru Komatsu and Satoshi Waguri},
  journal={Molecular and cellular biology},
  year={2014},
  volume={34 9},
  pages={
          1695-706
        }
}
Recent findings have suggested that the autophagic isolation membrane (IM) might originate from a domain of the endoplasmic reticulum (ER) called the omegasome. However, the morphological relationships between ER, omegasome, and IM remain unclear. In the present study, we found that hybrid structures composed of a double FYVE domain-containing protein 1 (DFCP1)-positive omegasome and the IM accumulated in Atg3-deficient mouse embryonic fibroblasts (MEFs). Moreover, correlative light and… CONTINUE READING
Highly Cited
This paper has 20 citations. REVIEW CITATIONS
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 12 citations