A cluster of patients with a chronic mononucleosis-like syndrome. Is Epstein-Barr virus the cause?

@article{Holmes1987ACO,
  title={A cluster of patients with a chronic mononucleosis-like syndrome. Is Epstein-Barr virus the cause?},
  author={Gary P. Holmes and Jonathan E. Kaplan and John A. Stewart and Bob Hunt and Paul F. Pinsky and Lawrence B. Schonberger},
  journal={JAMA},
  year={1987},
  volume={257 17},
  pages={2297-302}
}
A cluster of 134 patients who had undergone Epstein-Barr virus (EBV) serological testing because of suspected chronic EBV syndrome was investigated in Nevada. Fifteen case-patients were identified who had severe, persistent fatigue of undetermined etiology for more than two months. When compared with the remaining 119 patients who had less severe illnesses and with 30 age-, sex-, and race-matched control-persons, these 15 patients had significantly higher antibody titers against various… CONTINUE READING
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