A closer look at chemokines and their role in asthmatic responses.

  title={A closer look at chemokines and their role in asthmatic responses.},
  author={Joost J. Smit and Nicholas W Lukacs},
  journal={European journal of pharmacology},
  volume={533 1-3},
Inflammatory cell recruitment is a hallmark phenomenon of all inflammatory diseases, including allergic asthma. In allergy and asthma, recruitment of inflammatory cells such as T cells, dendritic cells, mast cells, eosinophils and neutrophils, is mediated via a number of chemokines and their receptors. Not only are chemokines involved in recruitment of these cells, they also play a role in activation and differentiation of inflammatory cells, among others, by selectively activating Th1 or Th2… CONTINUE READING

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