A close encounter of the third kind: monocyte-derived cells.

  title={A close encounter of the third kind: monocyte-derived cells.},
  author={Alexander Mildner and Simon Yona and Steffen Jung},
  journal={Advances in immunology},
Recent insights into discrete myeloid developmental pathways have provided critical information about the organization of the murine mononuclear phagocyte compartment. Short-lived dendritic cells (DCs) have been shown to continuously arise from dedicated bone marrow-derived precursors. In contrast, it is now appreciated that most tissue macrophage populations are established before birth and subsequently maintain themselves throughout adulthood by longevity and limited self-renewal. Both of… CONTINUE READING

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