A clinicopathological study of B-cell differentiation markers and transcription factors in classical Hodgkin's lymphoma: a potential prognostic role of MUM1/IRF4.

@article{Valsami2007ACS,
  title={A clinicopathological study of B-cell differentiation markers and transcription factors in classical Hodgkin's lymphoma: a potential prognostic role of MUM1/IRF4.},
  author={Serena I Valsami and Vassiliki Pappa and Dimitra Rontogianni and Frieda Kontsioti and Efstathios S Papageorgiou and J. G. Dervenoulas and Themis Karmiris and Sotirios Papageorgiou and Nikolaos Harhalakis and Nikolaos Xiros and Emmanuel Nikiforakis and Theofanis C. Economopoulos},
  journal={Haematologica},
  year={2007},
  volume={92 10},
  pages={1343-50}
}
BACKGROUND AND OBJECTIVES Although most patients with classical Hodgkin's lymphoma (CHL) are cured, a significant minority are refractory to treatment. The investigation of biological markers could improve the predictive capacity of clinical staging systems. The aim of our study was to detect B-cell differentiation markers and transcription factors in CHL in order to define subgroups with different histogeneses and prognoses. DESIGN AND METHODS We evaluated 107 cases of CHL for BCL6, CD79a… CONTINUE READING

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