A clinical study of LSD treatment in alcoholism.

  title={A clinical study of LSD treatment in alcoholism.},
  author={Arnold M. Ludwig and Jerome Levine and L H Stark and Roxana Lazăr},
  journal={The American journal of psychiatry},
  volume={126 1},
One hundred seventy-six male alcoholic patients participated in a controlled investigation of the differential efficacy of three LSD treatment procedures and a "no therapy," or milieu treatment, condition. Half of each group was also assigned to disulfiram after discharge from the hospital to determine whether any of these techniques could be enhanced by its use. Although significant improvement was shown within all treatment groups as measured by a number of clinical assessments in the post… 

Evaluation of Treatment Methods in Chronic Alcoholism

There was a rapid increase in the vogue for group as opposed to individual psychotherapy, and the introduction of tranquilizers and antidepressants came to the fore.

Treatment of alcoholism using psychedelic drugs: a review of the program of research.

  • M. Mangini
  • Psychology
    Journal of psychoactive drugs
  • 1998
The history of one branch of psychedelic research, the therapeutic use of LSD in the treatment of alcoholism, and of the events that led to the relabeling of the "hallucinogens" as drugs of abuse are explored.

LSD revisited. A ten-year follow-up of medical LSD use.

A follow-up survey of 247 persons who received d-lysergic acid diethylamide (LSD) in either an experimental (nonmedical) or Psychotherapeutic setting was made to determine the lasting effects, if

Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder

The results in this trial showed that psilocybin administered in combination with psychotherapy produced robust decreases in the percentage of heavy drinking days compared with those produced by active placebo and psychotherapy.

The experimental use of psychedelic (LSD) psychotherapy.

The history of research with psychedelic drugs has produced a variety of methods for their use and conflicting claims about results. First came the wave of excitement among experimentalists in the

Therapeutic Use of LSD in Psychiatry: A Systematic Review of Randomized-Controlled Clinical Trials

The evidence to date is strongest for the use of LSD in the treatment of alcoholism, and new studies that conform to modern standards are necessary in order to strengthen knowledge on its use and open new doors in the future.

Assessment of Posttreatment Follow-Up Evaluation Procedures with Alcohol-Abuse Patients: A Methodological Study

The purpose of this project was to clarify the methodological considerations involved in the posttreatment follow-up evaluation of alcohol-abuse patients and to answer the follow- up questions of how and when to measure treatment effects with discharged alcoholics.

Development of a Psychotherapeutic Model for Psilocybin-Assisted Treatment of Alcoholism

An overview of the history of psychedelic-assisted treatment is provided, what is known about the therapeutic mechanisms of these treatments are reviewed, and the various purposes of psychotherapy in the context of both research and clinical use are considered.

Classic hallucinogens in the treatment of addictions

Psilocybin-assisted treatment for alcohol dependence: A proof-of-concept study

A single-group proof-of-concept study to quantify acute effects of psilocybin in alcohol-dependent participants and to provide preliminary outcome and safety data, providing a strong rationale for controlled trials with larger samples to investigate efficacy and mechanisms.



The hypnodelic treatment technique.

  • J. LevineA. Ludwig
  • Psychology
    The International journal of clinical and experimental hypnosis
  • 1966
Hypnodelic therapy appears to be a useful technique, but many controlled and long-term follow-up studies will be necessary to determine its efficacy and usefulness compared with other forms of psychedelic and psychiatric therapy.


The present study was designed to compare in a controlled fashion therapeutic efficacy of hypnodelic therapy with four other brief treatmelt techniques employing different combinations of LSD, hypnosis, and '_otherapy.

The Breathalyzer and its Applications

The Breathalyzer was designed and developed by R. F. Borkenstein in 1954 for the analysis of alcohol in samples of breath and its method of operation and accuracy and its application in law enforcement is described.